Structural determination of the capsular polysaccharide antigen of type II group B Streptococcus.
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منابع مشابه
Structural determination and immunochemical characterization of the type V group B Streptococcus capsular polysaccharide.
The type V capsular polysaccharide of group B Streptococcus has been isolated and purified, and its repeating unit structure determined. The native type V polysaccharide contains D-glucose, D-galactose, 2-acetamido-2-deoxy-D-glucose, and sialic acid in a molar ratio of 3:2:1:1. Methylation analysis and 1H NMR and 13C NMR analysis of the native type V polysaccharide and of its specifically degra...
متن کاملIsolation and characterization of type IV group B Streptococcus capsular polysaccharide.
An antigenically distinct serotype, type IV, has recently been added to the recognized serotypes of group B streptococci (GBS). We isolated and purified the capsular polysaccharide antigen from a prototype type IV GBS strain. The type IV capsular polysaccharide formed a precipitin line with rabbit antiserum to type IV GBS organisms but not with antiserum to organisms of GBS serotype Ia, Ib, II,...
متن کاملFilamentous capsulated streptococci from the human respiratory tract. I. Antigenic attributes of provisional capsular type 83 and its relationship to streptococci of so-called group M.
Two immunologically reactive polysaccharides have been isolated from the cell walls and from culture filtrates of a filamentous alpha-hemolytic streptococcus provisionally designated capsular type 83. Both polysaccharides were purified by diethylaminoethyl-cellulose chromatography. Analysis indicates that the capsular polysaccharide consists of galactose and phosphorus, whereas the cell wall po...
متن کاملStructure of a protective epitope of group B Streptococcus type III capsular polysaccharide.
Despite substantial progress in the prevention of group B Streptococcus (GBS) disease with the introduction of intrapartum antibiotic prophylaxis, this pathogen remains a leading cause of neonatal infection. Capsular polysaccharide conjugate vaccines have been tested in phase I/II clinical studies, showing promise for further development. Mapping of epitopes recognized by protective antibodies ...
متن کاملفراوانی سروتایپ‌های کپسولی استرپتوکوکوس گروه B جدا شده از نمونه های بالینی بر اساس ژنوتایپینگ
Background: Group B Streptococci (GBS) or Streptococcus agalactiae is one of the most common causes of sepsis and meningitis in neonates and of invasive diseases in pregnant women. It can also cause infectious disease among adults with underlying medical conditions like immunocompromised individuals. Polysaccharide capsule is an important virulence factor. Nine GBS serotypes (Ia, Ib, II to VI...
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عنوان ژورنال:
- The Journal of biological chemistry
دوره 258 3 شماره
صفحات -
تاریخ انتشار 1983